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Egg Donation

An egg donor woman donates her eggs to an infertile couple, which are fertilized with the husband’s sperm, and resulting good grade embryos are transferred back to the wife’s uterus after optimal preparation.

Donor eggs offer women with ovarian failure or no ovaries the possibility of having children. This is a great way to help a couple achieve their dream of becoming parents.

Patients often resort to donor eggs as a last resort. It is crucial to fully understand the process before making a decision. Donor eggs will produce a healthy baby, and it is far cheaper than repeated unsuccessful attempts. Patients often have many questions and concerns when discussing donor egg procedures. Donor eggs are more likely to result in a pregnancy than any other treatment. This would allow more families to experience the joy of welcoming a baby into their lives. Sunflower Women's Hospital seeks to provide egg donation services with the consent and protection of the couple.

Egg Donation 1

Egg Donation 2

Indication

  • Advanced age of female partner(>40 years) is associated with a decline in quantity and quality of her eggs and hence decreased fertility.
  • Certain women suffer from decreased ovarian reserve( low AMH) even before they reach 40 years of age
  • Early onset of menopause (premature ovarian failure) which can occur in women as early as their 20’s or 30’s can require a woman to use donor eggs to grow her family.
  • Some women are born without ovaries or other reproductive organs. Sometimes a woman’s reproductive organs have been damaged due to disease or have been forced to have them surgically removed or those whose ovaries have been damaged by chemotherapy or radiotherapy which she may have undergone for cancer treatment.
  • Another indication would be a genetic disorder on part of the woman that can be over-comed by using eggs from healthy egg donor.
  • Many women have none of these issues, but continue to be unsuccessful using their own eggs (multiple IVF failure)

Congenital absence of eggs

Acquired reduced egg quantity / quality

Other

Donor screening

First, it will be necessary for the donor to undergo a thorough medical examination, including a pelvic exam, blood draw to check health status and to test for infectious diseases, and an ultrasound to examine her ovaries, uterus and other pelvic organs.

Our screening criteria

Legally anonymous

In India egg donations are legally anonymous as per ICMR guidelines, which means that neither egg donor nor infertile couple to whom she donates her eggs are known to each other. Neither is aware of other’s identity.

Donor matching & egg donor profiles

  • After donor is screened and deemed eligible for egg donation, she is matched to the recipient couple.
  • Matching involves allocating same blood group egg donor to the recipient
  • Recipient is allotted donor of similar physical characteristics – height, weight, complexion, hair colour, eye colour.
  • Recipients are provided with the matching donor’s profiles, among which they may select their preferred donor. Donor profile is provided in the following format : M1 form as per ICMR guidelines

Egg donation procedure

How Sunflower Women’s Hospital differs ?

Sunflower Women’s Hospital – success rates with donor egg in single embryo transfer attempt

Female partner age graph
Successful outcome with egg donation – IVF in case of couple with previous 3 children expired due to cystic fibrosis
  • A couple approached us after having lost three children within few days after birth from perfectly uneventful pregnancies.
  • Her third child was finally diagnosed to have cystic fibrosis.
  • When they consulted us, wife’s age was 38 years, on sonography and blood test she was diagnosed with decreased ovarian reserve.
  • Hence we discussed with the couple about egg donation IVF.
  • Next we ran targetted gene analysis of husband for cystic fibrosis and also did clinical exome of husband and egg donor to rule out presence of any other defective genes that may result in a child with genetic disorder.
  • Then we did egg donation IVF cycle, single blastocyst was transferred and resulted in a term birth of female child.

Healthy birth after premature menopause secondary to chemotherapy

Birth of healthy male and female twins to a woman who had undergone removal of both ovaries for borderline ovarian cancer.

  • A laboratory technician by profession consulted us with infertility and bilateral ovarian masses.
  • She underwent MRI and extensive blood investigation to determine nature of ovarian masses, and was then planned for staging exploratory laparotomy and bilateral salpingo-oophorectomy. A frozen section analysis was performed, which revealed the masses to be of borderline histopathology, hence uterus was preserved.
  • She later underwent egg donation IVF and concieved in her first embryo transfer attempt.
  • She delivered healthy twins at term via elective LSCS : one boy and one girl.

Birth of healthy male child to couple with one son affected with Duchenne muscular dystrophy(DMD).

  • A couple with one son affected with duchenne muscular dystrophy consulted us for further treatment.
  • His wife was a carrier of the disorder, which is X linked recessive. Since they were not very affording and could not afford ICSI with PGS( pre implantation genetic diagnosis), they took 2 more attempts at natural conception, but to their dismay each time they had an affected pregnancy (DMD) after determination with amniocentesis and terminated the same.
  • Since they were not affording they chose to opt for egg donation IVF.
  • She delivered a healthy male child at term.

Successful pregnancy in patient a super 47 XXX female with premature ovarian failure

  • A couple consulted us after 3 yrs of married life or infertility.
  • The female partner had primary amenorrhoea but had not undergone evaluation for same in detail.
  • When they consulted us we ran a couple of tests on her, she had 47 XXX on her chromosomal analysis which is one of the reasons for premature menopause.
  • Hence they underwent egg donation IVF with us.
  • She concieved in her second embryo transfer attempt and delivered a healthy female child.

Successful twin birth with egg donation IVF in a couple with history of repeated fertilisation failures.

  • A couple underwent 3 IVF-ICSI cycles with us, each time to land up with poor fertilisation and poor embryo formation.
  • Inspite of in depth evaulation for the same no cause could be determined.
  • Hence we offered them egg donation IVF.
  • They concieved in their first cycle of egg donation IVF.
  • She delivered healthy twins at 34 weeks, who were kept in NICU for 7 days and discharged home healthy.